rs1058808
A SNP in the ERBB2 gene on chromosome 17. Its most notable genotype is C;C: common in clinvar
- Gene
- ERBB2
- Location
- Chr 1739,727,784 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- AncestryDNA
- Minor allele frequency
- 49%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 4 HapMap populations.
- AverageC;C 60%
- European ancestry (Utah)C;C 6%
- Han Chinese (Beijing)C;C 69%
- Japanese (Tokyo)C;C 64%
- Yoruba (Nigeria)C;C 100%
Related
Notes
From SNPedia
Notes
Allelic imbalance in gene expression as a guide to cis-acting regulatory single nucleotide polymorphisms in cancer cells. Interactions among genes in the ErbB-Neuregulin signalling network are associated with increased susceptibility to schizophrenia. The genetic polymorphisms of HER-2 and the risk of lung cancer in a Korean population. Heritable variation of ERBB2 and breast cancer risk.
Source and license
Adapted from rs1058808 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.