rs1061147(A;A)

2.76x increased risk for Age Related Macular Degeneration.

Magnitude
2.2Worth knowing
Repute
Bad
Frequency
13%Average of 11 populations
On SNPedia
rs1061147(A;A)
Gene
CFH

Frequency

Share of people with A;A in each HapMap population.

  • Luhya (Kenya)30%
  • Maasai (Kenya)26%
  • African ancestry (Southwest US)19%
  • Tuscan18%
  • Yoruba (Nigeria)13%
  • European ancestry (Utah)12%
  • Gujarati Indian12%
  • Mexican ancestry (Los Angeles)10%
  • Han Chinese (Beijing)2%
  • Japanese (Tokyo)2%
  • Chinese (Denver)0%

Other genotypes of rs1061147

  1. A;CGoodNormal 0.97x risk for Age Related Macular Degeneration.Minor · 1.033% of people
  2. C;CGoodReduced 0.34x risk of Age Related Macular Degeneration.Worth knowing · 2.253% of people

All about rs1061147

Notes

From SNPedia

When the retina cells in the eye get damaged with age, it is known as Age Related Macular Degeneration. This SNP has about three times the normal risk. This SNP wrecks the brakes on the complementary immune system, so it can become out of control, resulting in inflamation that damages the cells in the eye. The SENS Research Foundation is working on a promising cure for Age Related Macular Degeneration: http://www.sens.org/outreach/conferences/lysosens-synthetic-biology-approach-treat-age-related-macular-degeneration

Source and license

Adapted from rs1061147(A;A) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.