rs1063192

A SNP in the CDKN2B gene on chromosome 9. Its most notable genotype is G;G: 0.71x reduced risk of myocardial infarction

Gene
CDKN2B
Location
Chr 922,003,368 (GRCh38)
Highest magnitude
1.5Minor
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
24%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. G;GMost notableGood0.71x reduced risk of myocardial infarctionMinor · 1.56% of people
  2. A;GGood0.71x reduced risk of myocardial infarctionMinor · 1.524% of people
  3. A;AGoodNormal risk of myocardial infarctionMinor · 1.070% of people

SNPedia records rs1063192 on the minus strand: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageG;G 6% A;G 24% A;A 70%
  • European ancestry (Utah)G;G 21% A;G 48% A;A 31%
  • Han Chinese (Beijing)G;G 5% A;G 30% A;A 64%
  • Japanese (Tokyo)G;G 5% A;G 26% A;A 69%
  • Yoruba (Nigeria)G;G 0% A;G 0% A;A 100%
  • African ancestry (Southwest US)G;G 0% A;G 7% A;A 93%
  • Chinese (Denver)G;G 4% A;G 31% A;A 65%
  • Gujarati IndianG;G 12% A;G 44% A;A 45%
  • Luhya (Kenya)G;G 0% A;G 2% A;A 98%
  • Mexican ancestry (Los Angeles)G;G 2% A;G 24% A;A 74%
  • Maasai (Kenya)G;G 0% A;G 6% A;A 94%
  • TuscanG;G 13% A;G 52% A;A 36%

Conditions, medicines and genes

Other CDKN2B SNPs

All CDKN2B SNPs

Notes

From SNPedia

Notes

rs1063192 is a SNP in the cyclin-dependent kinase inhibitor 2B CDKN2B gene. A study of 432 Han Chinese patients with myocardial infarctions concluded that male subjects carrying a rs1063192(C) allele were at 0.71x decreased risk (for MI). Myocardial Infarction

Source and license

Adapted from rs1063192 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.