Myocardial infarction

36 SNPs linked to Myocardial infarction across 19 genes, 6 with a genotype of magnitude 2 or higher.

Type: Condition
SNPs: 36
Notable: 6Magnitude 2 or higher
Well documented: 24
Genes: 19

Linked SNPs

Every genotype, as shown in 23andMe and AncestryDNA files.

rs5918ITGB3Worth knowing
- C;CMI risk, aspirin resistanceBad
- C;TMI risk, aspirin resistanceBad
- T;TaverageGood
rs1800888ADRB2Worth knowing
- C;CnormalGood
- C;Tincreased risk of coronary artery diseaseBad
- T;Tincreased risk of coronary artery diseaseBad
rs10757278Worth knowing
- A;A0.78x reduced risk for Coronary Heart Disease. 0.77x reduced risk for Brain Aneurysm and Abdominal Aortic Aneurysm.Good
- A;G1.3x risk for Heart Attack. Normal risk for Abdominal Aortic Aneurysm and Brain Aneurysm.Bad
- G;G1.6x risk for Heart Attack; 1.3x risk for Abdominal Aortic Aneurysm and Brain Aneurysm.Bad
rs708272CETPWorth knowing
- G;GSmall reduction in coronary heart disease risk from alcohol consumptionNot rated
- A;GSmall reduction in heart disease risk from drinking alcoholNot rated
- A;AB2B2 genotype; some reduction in heart disease risk from moderate alcohol consumptionGood
rs4665058BAZ2BWorth knowing
- A;A~4x increased risk among Europeans for sudden cardiac deathBad
- A;C2x increased risk among Europeans for sudden cardiac deathBad
- C;Ccommon in complete genomicsGood
rs662799APOA5Worth knowing
- A;AnormalGood
- A;G1.4x higher early heart attack risk; less weight gain on high fat dietsBad
- G;G2x higher early heart attack risk; less weight gain on high fat dietsBad
rs1010VAMP8Minor
- T;Tnormal risk of MINot rated
- C;T1.75x risk of MIBad
- C;C1.75x risk of MIBad
rs7025486DAB2IPMinor
- A;Aslight (1.4x) increase in risk for abdominal aortic aneurysm and other vascular disordersBad
- A;Gslight (1.2x) increase in risk for abdominal aortic aneurysm and some vascular disordersBad
- G;Gcommon/normalGood
rs1063192CDKN2BMinor
- G;G0.71x reduced risk of myocardial infarctionGood
- A;G0.71x reduced risk of myocardial infarctionGood
- A;ANormal risk of myocardial infarctionGood
rs1801020F12Minor
- G;GNormal risk of developing heart diseaseGood
- A;G1.31x increased risk of heart diseaseBad
- A;A1.31x increased risk of heart diseaseBad
rs4977574CDKN2B-AS1Minor
- A;AcommonGood
- A;GSome studies - but not others - report a slightly increased risk for myocardial infarctionBad
- G;GMost studies find a somewhat elevated (~1.5x) risk for myocardial infarctionBad
rs17465637MIA3Minor
- A;ANo summary available.Not rated
- A;C1.17x higher risk for myocardial infarctionBad
- C;C1.34x higher risk for myocardial infarctionBad
rs2291834MIA3Minor
- C;Cvery slightly higher risk for myocardial infarctionBad
- C;Tvery slightly higher risk for myocardial infarctionBad
- T;TnormalNot rated
rs20455KIF6Typical
- G;GNo summary available.Not rated
- A;GNo summary available.Not rated
- A;Acommon in clinvarGood
rs1333040CDKN2BASTypical
- C;CnormalNot rated
- C;T1.24x increased myocardial infarction risk, ~1.24x increased intracranial aneurysm riskBad
- T;T1.52x increased myocardial infarction risk, ~1.54x increased intracranial aneurysm riskBad
rs1799889SERPINE1Typical
- -;-MI riskNot rated
- -;GMI risk?Not rated
- G;Grisk for aneurysms?Not rated
rs1927911TLR4Typical
- G;GnormalNot rated
- A;G0.88x lower risk of nonfatal myocardial infarctionNot rated
- C;CNo summary available.Not rated
- A;A0.88x lower risk of nonfatal myocardial infarctionNot rated
rs2331291MIATTypical
- C;TNo summary available.Not rated
rs3025058MMP3Typical
- -;-5A/5A; higher MI risk?Not rated
- -;T5A/6ANot rated
- T;T6A/6A; higher CAD riskNot rated
rs4253623PPARATypical
- A;AnormalNot rated
- A;G1.25x higher risk of nonfatal myocardial infarctionNot rated
- G;G1.25x higher risk of nonfatal myocardial infarctionNot rated
rs4769874ALOX5APTypical
- G;GNo summary available.Good
rs10116277CDKN2B-AS1Typical
- G;TNo summary available.Not rated
rs10507391ALOX5APTypical
- A;AnormalNot rated
- A;T1.24x increased stroke risk for malesNot rated
- T;T1.24x increased stroke risk for malesNot rated
rs10757274CDKN2B-AS1Typical
- A;AnormalNot rated
- A;G~1.2x increased risk for heart diseaseBad
- G;G~1.3x increased risk for heart diseaseBad

Genes

Genosets

Gs194Myocardial Infarction RiskWorth knowing

Genosets combine several genotypes. Twofold checks them in your report.

Other SNPs

No notable genotype or detailed notes

Show 12 SNPs

Source and license

Adapted from Myocardial infarction on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.