rs708272(A;A)
B2B2 genotype; some reduction in heart disease risk from moderate alcohol consumption
- Magnitude
- 2.2Worth knowing
- Repute
- Good
- On SNPedia
- rs708272(T;T)Minus strand
- Gene
- CETP
Other genotypes of rs708272
Notes
From SNPedia
In the 2014 publication by Mehlig et al., (), this B2B2 genotype showed the greatest reduction in coronary heart disease risk for those drinking moderate amounts of alcohol (6.5 - 13g/day for men; odds ratio 0.21) compared to those imbibing low (under 6.5g) amounts (designated as the reference, i.e. odds ratio of 1). The odds ratios for B2B2 genotypes either abstaining or drinking higher amounts (over 13.5g/day) were also lower, at 0.76 and 0.48, respectively.
References
Related
Source and license
Adapted from rs708272(T;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.