rs708272(G;G)
Small reduction in coronary heart disease risk from alcohol consumption
- Magnitude
- 2.1Worth knowing
- Repute
- Not rated
- On SNPedia
- rs708272(C;C)Minus strand
- Gene
- CETP
Other genotypes of rs708272
Notes
From SNPedia
This is the genotype known as B1B1, and as reported in the Mehlig et al. 2014 article, () from a risk for coronary heart disease perspective this genotype does not show the large decrease in risk (odds ratio 0.21) from consuming alcohol seen in B2B2 patients. Hoever, intermediate amounts (6.5 - 13g of ethanol per day for men) of alcohol consumption were still associated with a somewhat reduced odds ratio (0.80) for both B1B1 and B1B2 genotypes compared to those with low (under 6.5g/day) ethanol intake. Abstainers and those drinking high amounts (over 13.5g/day) had slightly higher CHD risks compared to low amount drinkers, with odds ratios of 1.12 and 1.03, respectively.
References
Related
Source and license
Adapted from rs708272(C;C) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.