rs4769874
A SNP in the ALOX5AP gene on chromosome 13. Its most notable genotype is G;G.
- Gene
- ALOX5AP
- Location
- Chr 1330,752,304 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA
- Minor allele frequency
- 5%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageG;G 86%
- European ancestry (Utah)G;G 95%
- Han Chinese (Beijing)G;G 96%
- Japanese (Tokyo)G;G 97%
- Yoruba (Nigeria)G;G 78%
- African ancestry (Southwest US)G;G 74%
- Chinese (Denver)G;G 96%
- Gujarati IndianG;G 76%
- Luhya (Kenya)G;G 78%
- Mexican ancestry (Los Angeles)G;G 98%
- Maasai (Kenya)G;G 80%
- TuscanG;G 82%
Related
Conditions, medicines and genes
Notes
From SNPedia
Notes
rs4769874, also known as SG13S89, is an ALOX5AP gene SNP that has been defined as part of a haplotype potentially associated with risk for myocardial infarction or ischemic stroke. Details of this haplotype and several related studies are on the ALOX5AP page.
Source and license
Adapted from rs4769874 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.