rs1064795599

A SNP in the FBXL6 gene on chromosome 8. Its most notable genotype is T;T: Brown-Vialetto-Van Laere syndrome type 2 mutation; riboflavin treatment recommended

Gene
FBXL6
Location
Chr 8144,359,627 (GRCh38)
Highest magnitude
8.0Very important
Tested on
Not on consumer chips

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. G;GGoodcommon/normalTypical · 0.0
  2. G;TBadCarrier of a Brown-Vialetto-Van Laere syndrome type 2 mutationImportant · 3.0
  3. T;TMost notableBadBrown-Vialetto-Van Laere syndrome type 2 mutation; riboflavin treatment recommendedVery important · 8.0

On SNPedia: (G;G), (G;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Conditions, medicines and genes

Notes

From SNPedia

Notes

G;T

Unaffected carrier in absence of second mutation; see discussion at Brown-Vialetto-Van laere syndrome.

T;T

See discussion at Brown-Vialetto-Van laere syndrome, including recommendation for immediate riboflavin supplementation.

Source and license

Adapted from rs1064795599 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.