rs10821936(C;T)

Higher risk of childhood acute lymphoblastic leukemia

Magnitude
2.1Worth knowing
Repute
Bad
Frequency
42%Average of 11 populations
On SNPedia
rs10821936(C;T)
Gene
ARID5B

Frequency

Share of people with C;T in each HapMap population.

  • Mexican ancestry (Los Angeles)62%
  • Tuscan51%
  • Chinese (Denver)50%
  • Han Chinese (Beijing)45%
  • Gujarati Indian45%
  • Japanese (Tokyo)44%
  • European ancestry (Utah)43%
  • African ancestry (Southwest US)33%
  • Luhya (Kenya)30%
  • Maasai (Kenya)30%
  • Yoruba (Nigeria)24%

Other genotypes of rs10821936

  1. C;CMost notableBadHigher risk of childhood acute lymphoblastic leukemiaWorth knowing · 2.511% of people
  2. T;TNot ratednormalTypical · 0.048% of people

All about rs10821936

Notes

From SNPedia

Consistently, when we further classified children into age groups of those aged less than 5 years, those aged 5 to 10 years, and those aged greater than 10 years, there was a trend for decreasing allelic odds ratio (ie, relative risk of ALL conferred by each copy of the C allele at rs10821936) as age increased: 2.01 (95% CI = 1.85 to 2.19), 1.8 (95% CI = 1.6 to 2.02), and 1.48 (95% CI = 1.3 to 1.68), respectively. PMID 23512250

References

Source and license

Adapted from rs10821936(C;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.