rs10985112

A SNP in the C5 gene on chromosome 9. Its most notable genotype is G;G: common in complete genomics

Gene
C5
Location
Chr 9120,969,130 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
16%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. G;GMost notableGoodcommon in complete genomicsTypical · 0.067% of people

On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageG;G 67%
  • European ancestry (Utah)G;G 82%
  • Han Chinese (Beijing)G;G 90%
  • Japanese (Tokyo)G;G 99%
  • Yoruba (Nigeria)G;G 19%
  • African ancestry (Southwest US)G;G 30%
  • Chinese (Denver)G;G 94%
  • Gujarati IndianG;G 87%
  • Luhya (Kenya)G;G 24%
  • Mexican ancestry (Los Angeles)G;G 77%
  • Maasai (Kenya)G;G 41%
  • TuscanG;G 90%

Other C5 SNPs

All C5 SNPs

Notes

From SNPedia

Notes

rs10985112 increases susceptibility to Rheumatoid Arthritis 1.57 times for carriers of the A allele Genome-wide association study of rheumatoid arthritis by a score test based on wavelet transformation.

Source and license

Adapted from rs10985112 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.