rs17611

A SNP in the C5 gene on chromosome 9. Its most notable genotype is C;C: common in clinvar

Gene
C5
Location
Chr 9121,006,922 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
41%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. C;CMost notableGoodcommon in clinvarTypical · 0.044% of people

SNPedia records rs17611 on the minus strand: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 44%
  • European ancestry (Utah)C;C 38%
  • Han Chinese (Beijing)C;C 18%
  • Japanese (Tokyo)C;C 16%
  • Yoruba (Nigeria)C;C 100%
  • African ancestry (Southwest US)C;C 70%
  • Chinese (Denver)C;C 17%
  • Gujarati IndianC;C 11%
  • Luhya (Kenya)C;C 96%
  • Mexican ancestry (Los Angeles)C;C 28%
  • Maasai (Kenya)C;C 73%
  • TuscanC;C 22%

Conditions, medicines and genes

Other C5 SNPs

All C5 SNPs

Notes

From SNPedia

Notes

Although rs17611 was the only SNP to remain significant after multivariate analysis (odds ratio 0.585, p = 0.0037) in a study of 459 patients, ROC curve analysis did not show any contribution of this SNP to overall stroke risk.

Source and license

Adapted from rs17611 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.