rs11037909

A SNP in the EXT2 gene on chromosome 11. Its most notable genotype is T;T: 1.47x type II diabetes risk

Gene
EXT2
Location
Chr 1144,234,064 (GRCh38)
Highest magnitude
1.2Minor
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
30%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;TBad1.27x type II diabetes riskMinor · 1.134% of people
  2. T;TMost notableBad1.47x type II diabetes riskMinor · 1.256% of people

On SNPedia: (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;T 34% T;T 56%
  • European ancestry (Utah)C;T 32% T;T 56%
  • Han Chinese (Beijing)C;T 41% T;T 40%
  • Japanese (Tokyo)C;T 43% T;T 42%
  • Yoruba (Nigeria)C;T 24% T;T 73%
  • African ancestry (Southwest US)C;T 30% T;T 68%
  • Chinese (Denver)C;T 52% T;T 30%
  • Gujarati IndianC;T 42% T;T 43%
  • Luhya (Kenya)C;T 11% T;T 88%
  • Mexican ancestry (Los Angeles)C;T 48% T;T 29%
  • Maasai (Kenya)C;T 14% T;T 85%
  • TuscanC;T 32% T;T 61%

Other EXT2 SNPs

All EXT2 SNPs

Notes

From SNPedia

Notes

rs11037909 increases susceptibility to Type II Diabetes 1.27 times for heterozygotes (CT) and 1.47 times for homozygotes (TT)

Source and license

Adapted from rs11037909 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.