rs11164838

A SNP in the FAM69A gene on chromosome 1. Its most notable genotype is C;C: >1.11x risk

Gene
FAM69A
Location
Chr 192,929,821 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
44%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableBad>1.11x riskTypical · 0.043% of people
  2. C;TBad1.11x riskTypical · 0.033% of people
  3. T;TNot ratedcommonTypical · 0.024% of people

On SNPedia: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 43% C;T 33% T;T 24%
  • European ancestry (Utah)C;C 35% C;T 48% T;T 18%
  • Han Chinese (Beijing)C;C 6% C;T 32% T;T 62%
  • Japanese (Tokyo)C;C 8% C;T 31% T;T 61%
  • Yoruba (Nigeria)C;C 88% C;T 10% T;T 1%
  • African ancestry (Southwest US)C;C 66% C;T 32% T;T 2%
  • Chinese (Denver)C;C 7% C;T 39% T;T 54%
  • Gujarati IndianC;C 32% C;T 42% T;T 27%
  • Luhya (Kenya)C;C 86% C;T 14% T;T 0%
  • Mexican ancestry (Los Angeles)C;C 29% C;T 52% T;T 19%
  • Maasai (Kenya)C;C 88% C;T 11% T;T 1%
  • TuscanC;C 24% C;T 53% T;T 24%

Conditions, medicines and genes

Other FAM69A SNPs

All FAM69A SNPs

Notes

From SNPedia

Notes

rs11164838 has been reported in a large study to be associated with multiple sclerosis. The risk allele (oriented to the dbSNP entry) is (C); the odds ratio associated with this allele is 1.12 (CI 1.05-1.18).

Source and license

Adapted from rs11164838 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.