rs113954997

A SNP in the RRAS2 gene on chromosome 11. Its most notable genotype is A;T: Noonan syndrome 12 mutation (predicted)

Gene
RRAS2
Location
Chr 1114,294,844 (GRCh38)
Highest magnitude
8.1Very important
Tested on
AncestryDNA

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. T;TGoodcommon in complete genomicsTypical · 0.0
  2. A;TMost notableBadNoonan syndrome 12 mutation (predicted)Very important · 8.1

SNPedia records rs113954997 on the minus strand: (A;A), (A;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Notes

From SNPedia

Notes

aka c.215A>T (p.Gln72Leu) see also OMIM 600098.0001

A;T

see links via main rs-page

Source and license

Adapted from rs113954997 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.