rs115532916

A SNP in the ACAD9 gene on chromosome 3. Its most notable genotype is A;G: Carrier of a mt deficiency mutation

Gene
ACAD9
Location
Chr 3128,904,079 (GRCh38)
Highest magnitude
3.0Important
Tested on
AncestryDNA
Minor allele frequency
1%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;GMost notableBadCarrier of a mt deficiency mutationImportant · 3.0
  2. G;GGoodcommon in clinvarTypical · 0.0

On SNPedia: (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Notes

From SNPedia

Notes

aka c.976G>C (p.Ala326Pro or A326P) and also c.976G>A (p.Ala326Thr or A326T); the former is considered pathogenic in ClinVar for recessively inherited mitochondrial complex I deficiency due to ACAD9 deficiency, whereas the latter is most likely benign.

A;G

Unaffected in absence of a second ACAD9 gene mutation; see text and links via main rs-page

Source and license

Adapted from rs115532916 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.