rs117371763

A SNP. Its most notable genotype is C;T: Moderate (0.67x) reduction in gout susceptibility

Gene
None listed
Highest magnitude
2.0Worth knowing
Tested on
Not on consumer chips

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CGoodcommon/normalTypical · 0.0
  2. C;TMost notableGoodModerate (0.67x) reduction in gout susceptibilityWorth knowing · 2.0
  3. T;TGoodModerate (0.67x) reduction in gout susceptibilityWorth knowing · 2.0

On SNPedia: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Conditions, medicines and genes

Notes

From SNPedia

Notes

aka c.1129C>T (p.Arg377Cys or R377C) A 2020 paper studying ~500 Japanese gout patients found that the rs117371763(T) allele reduced odds of developing gout (OR 0.67, CI:0.53-0.85, pmeta=7.8×10e-4).

C;T

see text on main rs-page

T;T

see text on main rs-page

Source and license

Adapted from rs117371763 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.