rs118192224

A SNP in the KCNQ2 gene on chromosome 20. Its most notable genotype is A;G: Possible miscall; otherwise, benign familial neonatal seizure related mutation

Gene
KCNQ2
Location
Chr 2063,419,632 (GRCh38)
Highest magnitude
3.0Important
Tested on
AncestryDNA

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. G;GGoodcommon in clinvarTypical · 0.0
  2. A;GMost notableBadPossible miscall; otherwise, benign familial neonatal seizure related mutationImportant · 3.0

SNPedia records rs118192224 on the minus strand: (C;C), (C;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Notes

From SNPedia

Notes

A;G

Likely to be a miscall in Ancestry v2 datasets, but otherwise, this genotype contains a dominant mutation considered pathogenic for benign familial neonatal seizures.

Source and license

Adapted from rs118192224 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.