rs118203905
A SNP in the F5 gene on chromosome 1. Its most notable genotype is C;C: Hemophilia A (severity varies)
- Gene
- F5
- Location
- Chr 1169,555,300 (GRCh38)
- Highest magnitude
- 5.5Very important
- Tested on
- AncestryDNA
- Minor allele frequency
- <1%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
- T;TGoodcommon in clinvar
- C;TBadCarrier of a Factor V deficiency mutation
- C;CMost notableBadHemophilia A (severity varies)
SNPedia records rs118203905 on the minus strand: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other F5 SNPs
- rs6025T;T11.4x higher risk of thrombosisVery important
- rs118203906G;GHemophilia A (severity varies)Very important
- rs118203907C;CHemophilia A (severity varies)Very important
- rs118203908A;AHemophilia A (severity varies)Very important
- rs118203909A;AHemophilia A (severity varies)Very important
- rs118203910A;AHemophilia A (severity varies)Very important
- rs118203911G;GHemophilia A (severity varies)Very important
- rs118203912A;AHemophilia A (severity varies)Very important
Notes
From SNPedia
Notes
C;T
Usually unaffected in absence of a second F5 gene mutation
Source and license
Adapted from rs118203905 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.