rs11842874(A;A)

Common but +17% risk Osteoarthritis

Magnitude
1.8Minor
Repute
Bad
Frequency
72%Average of 11 populations
On SNPedia
rs11842874(A;A)
Gene
MCF2L

Frequency

Share of people with A;A in each HapMap population.

  • Gujarati Indian91%
  • European ancestry (Utah)87%
  • Tuscan86%
  • Mexican ancestry (Los Angeles)78%
  • African ancestry (Southwest US)75%
  • Chinese (Denver)73%
  • Maasai (Kenya)69%
  • Han Chinese (Beijing)65%
  • Japanese (Tokyo)65%
  • Luhya (Kenya)54%
  • Yoruba (Nigeria)52%

Other genotypes of rs11842874

  1. A;GBad+17% increased risk for osteoarthritisMinor · 1.225% of people
  2. G;GGoodreduced risk for osteoarthritisMinor · 1.43% of people

All about rs11842874

Notes

From SNPedia

risk 1.17 [1.11–1.23], p = 2.1 × 10−8

References

Source and license

Adapted from rs11842874(A;A) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.