rs121434393
A SNP in the TRPC6 gene on chromosome 11. Its most notable genotype is A;T: Focal segmental glomerulosclerosis 2
- Gene
- TRPC6
- Location
- Chr 11101,453,674 (GRCh38)
- Highest magnitude
- 3.5Important
- Tested on
- AncestryDNA
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
- T;TGoodcommon in clinvar
- A;TMost notableBadFocal segmental glomerulosclerosis 2
SNPedia records rs121434393 on the minus strand: (A;A), (A;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Conditions, medicines and genes
Other TRPC6 SNPs
- i5005218C;TFocal segmental glomerulosclerosis 2Important
- i5005219A;TFocal segmental glomerulosclerosis 2Important
- i5005220A;TFocal segmental glomerulosclerosis 2Important
- i5005221A;GFocal segmental glomerulosclerosis 2Important
- i5005222A;GFocal segmental glomerulosclerosis 2Important
- rs121434390G;TFocal segmental glomerulosclerosis 2Important
- rs121434391C;TFocal segmental glomerulosclerosis 2Important
- rs121434392A;TFocal segmental glomerulosclerosis 2Important
Notes
From SNPedia
Notes
Focal segmental glomerulosclerosis 2 Called i5005220 by 23andMe
A;T
See discussion at Focal segmental glomerulosclerosis
Source and license
Adapted from rs121434393 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.