rs121908007
A SNP in the SUOX gene on chromosome 12. Its most notable genotype is A;A: sulfite oxidase deficiency
- Gene
- SUOX
- Location
- Chr 1256,004,039 (GRCh38)
- Highest magnitude
- 5.0Very important
- Tested on
- 23andMe, AncestryDNA
Genotypes
As shown in 23andMe and AncestryDNA files.
- A;AMost notableBadsulfite oxidase deficiency
- A;GBadcarrier of a sulfite oxidase deficiency allele
- G;GGoodcommon in clinvar
On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Notes
From SNPedia
Notes
rs121908007, also known as R160Q, is a SNP in the sulfite oxidase SUOX gene. A report published in 1998 concluded that a patient suffering from sulfite oxidase deficiency inherited two copies of the rs121908007(A) allele. See also: OMIM 606887.0001
A;A
A 1998 publication concluded that this mutation (when two copies are inherited) leads to sulfite oxidase deficiency. See the main rs121908007 for more details.
A;G
You are a carrier of a single allele associated with sulfite oxidase deficiency, and are most likely unaffected. If you have inherited two copies, you would probably suffer from sulfite oxidase deficiency.
Source and license
Adapted from rs121908007 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.