rs202085145

A SNP in the SUOX gene on chromosome 12. Its most notable genotype is T;T: Sulfite oxidase deficiency (predicted)

Gene
SUOX
Location
Chr 1256,002,720 (GRCh38)
Highest magnitude
8.0Very important
Tested on
Not on consumer chips

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. G;GGoodcommon/normalTypical · 0.0
  2. G;TBadCarrier of sulfite oxidase deficiency mutation; possible effects?Important · 3.9
  3. T;TMost notableBadSulfite oxidase deficiency (predicted)Very important · 8.0

On SNPedia: (G;G), (G;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other SUOX SNPs

All SUOX SNPs

Notes

From SNPedia

Notes

aka c.228G>T, p.Arg76Ser, R76S ClinVar indicated "uncertain significance" for sulfite oxidase deficiency, also known as Sulfocysteinuria, listed in OMIM as a recessively inherited condition; in , this variant appears to have some effect even if inherited in only one copy (see paper for discussion).

G;T

Presumably unaffected in absence of a second SUOX gene mutation, however, see potential effects discussed in article cited in text on main rs-page.

T;T

see discussion and links via main rs-page

Source and license

Adapted from rs202085145 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.