rs121908677

A SNP in the SLC7A7 gene on chromosome 14. Its most notable genotype is A;C: Carrier of a lysinuric protein intolerance mutation

Gene
SLC7A7
Location
Chr 1422,813,238 (GRCh38)
Highest magnitude
3.0Important
Tested on
Not on consumer chips

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. C;CGoodcommon in clinvarTypical · 0.0
  2. A;CMost notableBadCarrier of a lysinuric protein intolerance mutationImportant · 3.0

SNPedia records rs121908677 on the minus strand: (G;G), (G;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Notes

From SNPedia

Notes

aka c.161G>T (p.Gly54Val or G54V)

A;C

Unaffected in absence of a second SLC7A7 gene mutation

Source and license

Adapted from rs121908677 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.