rs121912472

A SNP in the INSL6 gene on chromosome 9. Its most notable genotype is C;C: JAK2-K607N variant

Gene
INSL6
Location
Chr 95,073,742 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
AncestryDNA

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableBadJAK2-K607N variantWorth knowing · 2.0
  2. C;GBadJAK2-K607N variantWorth knowing · 2.0
  3. G;GGoodcommon in clinvarTypical · 0.0

On SNPedia: (C;C), (C;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Conditions, medicines and genes

Other INSL6 SNPs

All INSL6 SNPs

Notes

From SNPedia

Notes

rs121912472, also known as Lys607Asn, is a variant likely to be acquired (i.e. somatic) in the Janus kinase 2 JAK2 gene. The (rare) rs121912472(C) variant may be associated with certain myeloproliferative disorders. See: OMIM 147796.0002

C;C

See rs121912472 for discussion.

C;G

See rs121912472 for discussion.

Source and license

Adapted from rs121912472 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.