rs121912763
A SNP in the RHD gene on chromosome 1. Its most notable genotype is T;T: common in clinvar
- Gene
- RHD
- Location
- Chr 125,303,329 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- AncestryDNA
- Minor allele frequency
- <1%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Notes
From SNPedia
Notes
rs121912763 is a polymorphism in the RHD gene known as weak Rh D, and formerly known as D(u). A total of 16 different molecular weak D types plus 2 alleles characteristic of partial D have been identified. Most, if not all, weak D phenotypes carry altered RhD proteins, suggesting a causal relationship. Genotyping of weak D may guide Rhesus-negative transfusion policy for such molecular weak D types that were prone to develop anti-D, and who risk transfusion reactions if transfused with Rh D positive blood.
Source and license
Adapted from rs121912763 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.