rs121912998
A SNP in the DSP gene on chromosome 6. Its most notable genotype is A;G: Significance unclear: formerly associated with cardiomyopathy
- Gene
- DSP
- Location
- Chr 67,542,003 (GRCh38)
- Highest magnitude
- 2.0Worth knowing
- Tested on
- AncestryDNA
- Minor allele frequency
- <1%
Genotypes
As shown in 23andMe and AncestryDNA files.
- A;GMost notableNot ratedSignificance unclear: formerly associated with cardiomyopathy
- G;GGoodcommon in clinvar
On SNPedia: (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other DSP SNPs
- rs121912999A;GArrhythmogenic right ventricular dysplasiaVery important
- rs397516919A;GArrhythmogenic right ventricular dysplasiaVery important
- rs397516923C;TArrhythmogenic right ventricular dysplasiaVery important
- rs397516929C;TArrhythmogenic right ventricular dysplasiaVery important
- rs397516933C;TArrhythmogenic right ventricular dysplasiaVery important
- rs397516946C;TArrhythmogenic right ventricular dysplasiaVery important
- rs727502993-;ACArrhythmogenic right ventricular dysplasiaVery important
- rs727503000-;AArrhythmogenic right ventricular dysplasiaVery important
Notes
From SNPedia
Notes
A;G
Originally reported to be associated with arrhythmogenic right ventricular dysplasia (ARVD8) and cardiomyopathy, but significance is now considered unclear; ClinVar lists it as pathogenic at last check.
Source and license
Adapted from rs121912998 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.