rs121918042
A SNP in the PKD2 gene on chromosome 4. Its most notable genotype is C;T: Polycystic kidney disease, autosomal dominant form (predicted)
- Gene
- PKD2
- Location
- Chr 488,046,712 (GRCh38)
- Highest magnitude
- 5.0Very important
- Tested on
- AncestryDNA
Genotypes
As shown in 23andMe and AncestryDNA files.
- C;CGoodcommon in clinvar
- C;TMost notableBadPolycystic kidney disease, autosomal dominant form (predicted)
On SNPedia: (C;C), (C;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other PKD2 SNPs
- rs58606740A;GPolycystic kidney disease, autosomal dominant form (predicted)Very important
- rs121918039A;GPolycystic kidney disease, autosomal dominant form (predicted)Very important
- rs121918040C;TPolycystic kidney disease, autosomal dominant form (predicted)Very important
- rs121918041C;TPolycystic kidney disease, autosomal dominant form (predicted)Very important
- rs121918043A;TPolycystic kidney disease, autosomal dominant form (predicted)Very important
- rs145877597A;GPolycystic kidney disease, autosomal dominant form (predicted)Very important
- rs146396414C;TPolycystic kidney disease, autosomal dominant form (predicted)Very important
- rs200001068C;TPolycystic kidney disease, autosomal dominant form (predicted)Very important
Notes
From SNPedia
Notes
aka c.1390C>T (p.Arg464Ter) 23andMe name: i5002464
Source and license
Adapted from rs121918042 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.