rs121918481

A SNP in the F2 gene on chromosome 11. Its most notable genotype is C;C: Increased risk of dysprothrombinemia. Prothrombin Himi 1.

Gene
F2
Location
Chr 1146,728,004 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
AncestryDNA

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableBadIncreased risk of dysprothrombinemia. Prothrombin Himi 1.Worth knowing · 2.0
  2. T;TGoodNormal. Not prothrombin Himi 1.Typical · 0.1

On SNPedia: (C;C), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other F2 SNPs

All F2 SNPs

Notes

From SNPedia

Notes

C;C

May require another mutation (Himi 2) to have any effect. May cause decreased blood clotting.

Source and license

Adapted from rs121918481 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.