rs121918517

A SNP in the PRKCG gene on chromosome 19. Its most notable genotype is A;G: spinocerebellar ataxia 14 possible

Gene
PRKCG
Location
Chr 1953,898,100 (GRCh38)
Highest magnitude
5.0Very important
Tested on
AncestryDNA

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AGoodcommon in clinvarTypical · 0.0
  2. A;GMost notableBadspinocerebellar ataxia 14 possibleVery important · 5.0

On SNPedia: (A;A), (A;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Conditions, medicines and genes

Other PRKCG SNPs

All PRKCG SNPs

Notes

From SNPedia

Notes

rs121908517, also known as c.1081A>G, p.Ser361Gly or S361G, is a SNP in the PRKCG gene on chromosome 19. Based on one publication, the rare rs121908517(G) allele is reported to lead in a dominant manner to spinocerebellar ataxia, type 14. See OMIM or ClinVar for details.

A;G

see discussion at rs121918517

Source and license

Adapted from rs121918517 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.