rs12340895(C;G)

Increased odds (2 fold?) of developing V617F-positive MPN

Magnitude
2.5Worth knowing
Repute
Bad
Frequency
38%Average of 11 populations
On SNPedia
rs12340895(C;G)
Gene
INSL6

Frequency

Share of people with C;G in each HapMap population.

  • Mexican ancestry (Los Angeles)55%
  • Tuscan44%
  • Chinese (Denver)44%
  • European ancestry (Utah)43%
  • Maasai (Kenya)38%
  • Japanese (Tokyo)37%
  • Han Chinese (Beijing)36%
  • Gujarati Indian32%
  • African ancestry (Southwest US)32%
  • Luhya (Kenya)28%
  • Yoruba (Nigeria)24%

Other genotypes of rs12340895

  1. C;CGoodNo summary available.Typical · 0.058% of people
  2. G;GMost notableBad2 - 4 fold increased odds of developing V617F-positive MPNImportant · 3.55% of people

All about rs12340895

Source and license

Adapted from rs12340895(C;G) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.