rs12953717(C;T)

1.11x increased risk for colorectal cancer

Magnitude
0.0Typical
Repute
Not rated
Frequency
37%Average of 11 populations
On SNPedia
rs12953717(C;T)
Gene
SMAD7

Frequency

Share of people with C;T in each HapMap population.

  • Tuscan47%
  • Mexican ancestry (Los Angeles)47%
  • European ancestry (Utah)45%
  • Gujarati Indian45%
  • Chinese (Denver)39%
  • Han Chinese (Beijing)36%
  • Yoruba (Nigeria)35%
  • African ancestry (Southwest US)33%
  • Maasai (Kenya)30%
  • Luhya (Kenya)26%
  • Japanese (Tokyo)26%

Other genotypes of rs12953717

  1. C;CMost notableNot rated1.37x increased risk for colorectal cancerTypical · 0.053% of people
  2. T;TBad1x normal risk for colorectal cancerTypical · 0.010% of people

All about rs12953717

Source and license

Adapted from rs12953717(C;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.