rs12960

A SNP in the SPG7 gene on chromosome 16. Its most notable genotype is G;G: common in clinvar

Gene
SPG7
Location
Chr 1689,553,920 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, FamilyTreeDNA
Minor allele frequency
12%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. G;GMost notableGoodcommon in clinvarTypical · 0.083% of people

On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 8 HapMap populations.

  • AverageG;G 83%
  • European ancestry (Utah)G;G 72%
  • Han Chinese (Beijing)G;G 78%
  • Japanese (Tokyo)G;G 84%
  • Yoruba (Nigeria)G;G 100%
  • African ancestry (Southwest US)G;G 89%
  • Gujarati IndianG;G 71%
  • Mexican ancestry (Los Angeles)G;G 76%
  • Maasai (Kenya)G;G 97%

Other SPG7 SNPs

All SPG7 SNPs

Source and license

Adapted from rs12960 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.