rs13153971

A SNP in the SLC6A7 gene on chromosome 5. Its most notable genotype is C;C: 1.58x higher risk of Asthma.

Gene
SLC6A7
Location
Chr 5150,201,758 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
36%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableBad1.58x higher risk of Asthma.Worth knowing · 2.013% of people
  2. C;TBadNormal (higher) risk of Asthma.Worth knowing · 2.043% of people
  3. T;TGoodLower 0.63x risk of Asthma.Minor · 1.944% of people

On SNPedia: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 13% C;T 43% T;T 44%
  • European ancestry (Utah)C;C 19% C;T 58% T;T 24%
  • Han Chinese (Beijing)C;C 15% C;T 34% T;T 50%
  • Japanese (Tokyo)C;C 8% C;T 41% T;T 51%
  • Yoruba (Nigeria)C;C 4% C;T 32% T;T 64%
  • African ancestry (Southwest US)C;C 9% C;T 51% T;T 40%
  • Chinese (Denver)C;C 10% C;T 39% T;T 51%
  • Gujarati IndianC;C 20% C;T 42% T;T 39%
  • Luhya (Kenya)C;C 6% C;T 39% T;T 55%
  • Mexican ancestry (Los Angeles)C;C 16% C;T 33% T;T 52%
  • Maasai (Kenya)C;C 15% C;T 50% T;T 35%
  • TuscanC;C 19% C;T 54% T;T 28%

Conditions, medicines and genes

Notes

From SNPedia

Notes

Asthma

C;C

This (C;C) has 2.5x the risk compared to T;T (common for non-white people), or 1.58x the risk compared to C;T (normal for white people). Tested in Koreans.

C;T

This is normal for white people. But this (C;T) has 1.58x the risk compared to T;T (normal for non-white people). Tested in Koreans.

T;T

This was tested in Koreans.

Source and license

Adapted from rs13153971 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.