rs1361600

A SNP in the F3 gene on chromosome 1. Its most notable genotype is C;C: ~2x increased risk for adult-onset asthma in Japanese populations

Gene
F3
Location
Chr 194,542,362 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
44%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. T;TNot ratedNo summary available.Typical · 0.034% of people
  2. C;CMost notableBad~2x increased risk for adult-onset asthma in Japanese populationsWorth knowing · 2.021% of people

SNPedia records rs1361600 on the minus strand: (A;A), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageT;T 34% C;C 21%
  • European ancestry (Utah)T;T 31% C;C 22%
  • Han Chinese (Beijing)T;T 57% C;C 3%
  • Japanese (Tokyo)T;T 69% C;C 3%
  • Yoruba (Nigeria)T;T 11% C;C 37%
  • African ancestry (Southwest US)T;T 11% C;C 30%
  • Chinese (Denver)T;T 67% C;C 2%
  • Gujarati IndianT;T 42% C;C 12%
  • Luhya (Kenya)T;T 11% C;C 48%
  • Mexican ancestry (Los Angeles)T;T 38% C;C 17%
  • Maasai (Kenya)T;T 17% C;C 35%
  • TuscanT;T 19% C;C 25%

Conditions, medicines and genes

Notes

From SNPedia

Notes

rs1361600, also known as -603A>G, is a SNP in the promoter region of the coagulation factor III (aka thromboplastin or tissue factor) F3 gene. Two unrelated Japanese populations both showed an association between rs1361600(G;G) and adult-onset asthma, with an odds ratio of ~2 (p=.02 or .06).

Source and license

Adapted from rs1361600 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.