rs137852339
A SNP in the G6PD gene on chromosome X. Its most notable genotype is T;T: G6PD deficiency
- Gene
- G6PD
- Location
- Chr X154,533,044 (GRCh38)
- Highest magnitude
- 5.0Very important
- Tested on
- Not on consumer chips
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
- T;TMost notableBadG6PD deficiency
- C;TBadCarrier of G6PD deficiency mutation; variable expressivity
- C;CGoodcommon in clinvar
SNPedia records rs137852339 on the minus strand: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other G6PD SNPs
- rs5030868A;AHomozygous/Hemizygous mutantVery important
- rs5030869T;TG6PD deficiencyVery important
- rs5030872A;AG6PD deficiencyVery important
- rs72554664T;TG6PD deficiencyVery important
- rs72554665G;GG6PD deficiencyVery important
- rs76645461G;GG6PD deficiencyVery important
- rs76723693G;GG6PD deficiency; Hb1Ac value may need adjusting for diabetes diagnosisVery important
- rs78365220G;GG6PD deficiencyVery important
Notes
From SNPedia
Notes
aka c.949G>A, c.1039G>A, (p.Glu317Lys or E317K) G6PD Kerala-Kalyan 23andMe name: i5008450
T;T
Even if asymptomatic, consider being tested for G6PD deficiency and be aware of hemolytic anemia potential when taking certain drugs. See G6PD gene page for more information.
C;T
Carrier but likely to be asymptomatic. However, effects vary in females due to random X chromosome inactivation.
Source and license
Adapted from rs137852339 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.