rs137853096

A SNP in the HSD17B4 gene on chromosome 5. Its most notable genotype is A;A: DBP deficiency (predicted)

Gene
HSD17B4
Location
Chr 5119,452,621 (GRCh38)
Highest magnitude
7.0Very important
Tested on
AncestryDNA

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableBadDBP deficiency (predicted)Very important · 7.0
  2. A;GBadCarrier of a DBP deficiency mutationImportant · 3.0
  3. G;GGoodcommon in clinvarTypical · 0.0

On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other HSD17B4 SNPs

All HSD17B4 SNPs

Notes

From SNPedia

Notes

aka c.46G>A (p.Gly16Ser or G16S) 23andMe name: i5007145

A;A

see text and links via main rs-page

A;G

Unaffected in absence of a second HSD17B4 gene mutation

Source and license

Adapted from rs137853096 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.