rs137853146

A SNP in the ADAMTS2 gene on chromosome 5. Its most notable genotype is A;G: Carrier of an Ehlers-Danlos syndrome type VII mutation

Gene
ADAMTS2
Location
Chr 5179,272,926 (GRCh38)
Highest magnitude
3.0Important
Tested on
23andMe, AncestryDNA

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. G;GGoodcommon in clinvarTypical · 0.0
  2. A;GMost notableBadCarrier of an Ehlers-Danlos syndrome type VII mutationImportant · 3.0

SNPedia records rs137853146 on the minus strand: (C;C), (C;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other ADAMTS2 SNPs

All ADAMTS2 SNPs

Notes

From SNPedia

Notes

aka c.673C>T (p.Gln225Ter or Q225X)

A;G

Unaffected in absence of a second ADAMTS2 gene mutation

Source and license

Adapted from rs137853146 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.