rs1398009943

A SNP. Its most notable genotype is A;G: Reported to be associated with thyroid cancer

Gene
None listed
Highest magnitude
6.0Very important
Tested on
Not on consumer chips

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AGoodcommon/normalTypical · 0.0
  2. A;GMost notableBadReported to be associated with thyroid cancerVery important · 6.0

On SNPedia: (A;A), (A;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Conditions, medicines and genes

Notes

From SNPedia

Notes

aka Y1203H or p.Tyr1203His Reported to be a mutation in the DUOX2 gene, encoding a protein found in the thyroid gland and associated with dominantly inherited familial non-medullary thyroid cancer (FNMTC) based on an analysis of a family including 8 individuals diagnosed with thyroid cancer across 4 generations.

A;G

see text and links via main rs-page

Source and license

Adapted from rs1398009943 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.