rs1494555

A SNP in the IL7R gene on chromosome 5. Its most notable genotype is G;G: common in clinvar

Gene
IL7R
Location
Chr 535,871,088 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
33%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. G;GMost notableGoodcommon in clinvarTypical · 0.013% of people
  2. A;GGoodNo summary available.Typical · 0.040% of people
  3. A;AGoodbenign polymorphismTypical · 0.047% of people

SNPedia records rs1494555 on the minus strand: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageG;G 13% A;G 40% A;A 47%
  • European ancestry (Utah)G;G 8% A;G 42% A;A 50%
  • Han Chinese (Beijing)G;G 24% A;G 54% A;A 22%
  • Japanese (Tokyo)G;G 26% A;G 52% A;A 22%
  • Yoruba (Nigeria)G;G 1% A;G 8% A;A 91%
  • African ancestry (Southwest US)G;G 4% A;G 28% A;A 68%
  • Chinese (Denver)G;G 26% A;G 49% A;A 26%
  • Gujarati IndianG;G 25% A;G 48% A;A 28%
  • Luhya (Kenya)G;G 2% A;G 15% A;A 84%
  • Mexican ancestry (Los Angeles)G;G 16% A;G 68% A;A 16%
  • Maasai (Kenya)G;G 3% A;G 31% A;A 66%
  • TuscanG;G 8% A;G 50% A;A 42%

Other IL7R SNPs

All IL7R SNPs

Notes

From SNPedia

Notes

rs1494555, also known as Ile138Val or Val138Ile, is a SNP in the fourth exon of the IL7R interleukin 7 receptor gene. See the discussion for rs1494558 for this SNP's unclear association with a form of immunodeficiency.

Source and license

Adapted from rs1494555 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.