rs1535435

A SNP in the AHI1 gene on chromosome 6. Its most notable genotype is A;A.

Gene
AHI1
Location
Chr 6135,435,884 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
21%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableNot ratedNo summary available.Typical · 0.017% of people
  2. A;GNot ratedNo summary available.Typical · 0.024% of people
  3. G;GNot ratedNo summary available.Typical · 0.059% of people

On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 17% A;G 24% G;G 59%
  • European ancestry (Utah)A;A <1% A;G 13% G;G 86%
  • Han Chinese (Beijing)A;A <1% A;G 13% G;G 86%
  • Japanese (Tokyo)A;A 0% A;G 12% G;G 89%
  • Yoruba (Nigeria)A;A 46% A;G 42% G;G 12%
  • African ancestry (Southwest US)A;A 39% A;G 39% G;G 23%
  • Chinese (Denver)A;A <1% A;G 14% G;G 85%
  • Gujarati IndianA;A 0% A;G 24% G;G 76%
  • Luhya (Kenya)A;A 53% A;G 36% G;G 11%
  • Mexican ancestry (Los Angeles)A;A 0% A;G 22% G;G 78%
  • Maasai (Kenya)A;A 46% A;G 45% G;G 10%
  • TuscanA;A 1% A;G 7% G;G 92%

Conditions, medicines and genes

Other AHI1 SNPs

All AHI1 SNPs

Notes

From SNPedia

Notes

Originally reported to be associated with type-2 diabetes in a genome-wide association study; yet then reported not to be associated with either T2D or related metabolic traits in a large Danish population (ultimately 17,000 patients for the latter study). Type 2 diabetes whole-genome association study in four populations: the DiaGen consortium.

Source and license

Adapted from rs1535435 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.