rs1540771

A SNP in the LOC105374875 gene on chromosome 6. Its most notable genotype is T;T: common in complete genomics

Gene
LOC105374875
Location
Chr 6466,033 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA
Minor allele frequency
35%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. T;TMost notableGoodcommon in complete genomicsTypical · 0.011% of people

SNPedia records rs1540771 on the minus strand: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageT;T 11%
  • European ancestry (Utah)T;T 26%
  • Han Chinese (Beijing)T;T 5%
  • Japanese (Tokyo)T;T 12%
  • Yoruba (Nigeria)T;T 0%
  • African ancestry (Southwest US)T;T 5%
  • Chinese (Denver)T;T 8%
  • Gujarati IndianT;T 13%
  • Luhya (Kenya)T;T <1%
  • Mexican ancestry (Los Angeles)T;T 22%
  • Maasai (Kenya)T;T 3%
  • TuscanT;T 24%

Other LOC105374875 SNPs

All LOC105374875 SNPs

Notes

From SNPedia

Notes

plos the association between rs12203592 and hair color was independent of rs1540771, a SNP between the IRF4 and EXOC2 genes previously found to be associated with hair color.

Source and license

Adapted from rs1540771 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.