rs1557229683

A SNP. Its most notable genotype is A;A: G6PD deficiency

Gene
None listed
Highest magnitude
5.0Very important
Tested on
Not on consumer chips

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. G;GGoodcommon/normalTypical · 0.0
  2. A;GBadCarrier of G6PD deficiency mutation; variable expressivityImportant · 3.0
  3. A;AMost notableBadG6PD deficiencyVery important · 5.0

SNPedia records rs1557229683 on the minus strand: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Conditions, medicines and genes

Notes

From SNPedia

Notes

aka c.1187C>T, c.1277C>T, (p.Pro396Leu or P396L)

A;G

Carrier but likely to be asymptomatic. However, effects vary in females due to random X chromosome inactivation.

A;A

Even if asymptomatic, consider being tested for G6PD deficiency and be aware of hemolytic anemia potential when taking certain drugs. See G6PD gene page for more information.

Source and license

Adapted from rs1557229683 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.