rs1570360

This position is referred to as the -1154 position in many VEGF-associated publications. The normal (or wild type) form of this SNP is a (G). The (A) form reduces the activity of this gene, resulting in less VEGF protein. Individuals with one or more rs1570360(A) alleles are reported to be at about a 3 fold higher risk of developing Sudden Infant Death Syndrome . A functional variant of vascular endothelial growth factor is associated with severe ischemic complications in giant cell arteritis. Analysis of vascular endothelial growth factor (VEGF) functional variants in rheumatoid arthritis. Association between functional haplotypes of vascular endothelial growth factor and renal complications in Henoch-Schonlein purpura. Polymorphisms in the vascular endothelial growth factor gene and breast cancer in the Cancer Prevention Study II cohort. Functional variation in VEGF is not associated with type 2 diabetes in a United Kingdom Caucasian population. Possible gender-dependent association of vascular endothelial growth factor (VEGF) gene and ALS. VEGF, FGF1, FGF2 and EGF gene polymorphisms and psoriatic arthritis. Large-scale evaluation of candidate genes identifies associations between VEGF polymorphisms and bladder cancer risk. VEGF C-634G polymorphism is associated with protection from isolated ventricular septal defect: case-control and TDT studies. VEGF polymorphisms are associated with severity of diabetic retinopathy. Analysis of germline variants in CDH1, IGFBP3, MMP1, MMP3, STK15 and VEGF in familial and sporadic renal cell carcinoma. A systematic meta-analysis of genetic association studies for diabetic retinopathy. An analysis of growth, differentiation and apoptosis genes with risk of renal cancer. The role of vascular endothelial growth factor SNPs as predictive and prognostic markers for major solid tumors. No association of VEGF polymorphims with Alzheimer's disease. VEGFA polymorphisms and cardiovascular anomalies in 22q11 microdeletion syndrome: a case-control and family-based study. Pazopanib-induced hyperbilirubinemia is associated with Gilbert's syndrome UGT1A1 polymorphism. Association of vascular endothelial growth factor polymorphisms with nonproliferative and proliferative diabetic retinopathy. Human genetics of diabetic retinopathy: current perspectives. Gene polymorphism of vascular endothelial growth factor -1154 G>A is associated with hypertensive nephropathy in a Hispanic population. Association of polymorphisms/haplotypes of the genes encoding vascular endothelial growth factor and its KDR receptor with recurrent pregnancy loss. Genetics of VEGF serum variation in human isolated populations of cilento: importance of VEGF polymorphisms. Vascular endothelial growth factor A and cardiovascular disease in rheumatoid arthritis patients. Contribution of VEGF polymorphisms to variation in VEGF serum levels in a healthy population.