rs1592377

A SNP in the GRM8 gene on chromosome 7. Its most notable genotype is A;A.

Gene
GRM8
Location
Chr 7127,251,397 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, FamilyTreeDNA
Minor allele frequency
23%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableGoodNo summary available.Typical · 0.063% of people
  2. A;CNot ratedNo summary available.Typical · 0.031% of people

On SNPedia: (A;A), (A;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 4 HapMap populations.

  • AverageA;A 63% A;C 31%
  • European ancestry (Utah)A;A 55% A;C 37%
  • Han Chinese (Beijing)A;A 82% A;C 18%
  • Japanese (Tokyo)A;A 91% A;C 9%
  • Yoruba (Nigeria)A;A 25% A;C 62%

Other GRM8 SNPs

All GRM8 SNPs

Source and license

Adapted from rs1592377 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.