rs17864092

A SNP in the GRM8 gene on chromosome 7. Its most notable genotype is T;T: common in complete genomics

Gene
GRM8
Location
Chr 7126,999,550 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
11%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. T;TMost notableGoodcommon in complete genomicsTypical · 0.079% of people

On SNPedia: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageT;T 79%
  • European ancestry (Utah)T;T 73%
  • Han Chinese (Beijing)T;T 99%
  • Japanese (Tokyo)T;T 97%
  • Yoruba (Nigeria)T;T 82%
  • African ancestry (Southwest US)T;T 72%
  • Chinese (Denver)T;T 98%
  • Gujarati IndianT;T 75%
  • Luhya (Kenya)T;T 61%
  • Mexican ancestry (Los Angeles)T;T 71%
  • Maasai (Kenya)T;T 62%
  • TuscanT;T 80%

Other GRM8 SNPs

All GRM8 SNPs

Notes

From SNPedia

Notes

rs17864092 is a SNP in the glutamate receptor, metabotropic 8 GRM8 gene, encoding a metabotropic receptor for glutamate, a major excitatory neurotransmitter in the central nervous system. A genome-wide association study and an accompanying meta-analysis found some evidence for SNPs in the GRM8 gene, most notably rs17864092, and trait depression (p = 5 x 10e-6).

Source and license

Adapted from rs17864092 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.