rs1625895
A SNP in the TP53 gene on chromosome 17. Its most notable genotype is T;T: common in clinvar
- Gene
- TP53
- Location
- Chr 177,674,797 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 14%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs1625895 on the minus strand: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageT;T 5%
- European ancestry (Utah)T;T 0%
- Han Chinese (Beijing)T;T 0%
- Japanese (Tokyo)T;T 0%
- Yoruba (Nigeria)T;T 8%
- African ancestry (Southwest US)T;T 7%
- Chinese (Denver)T;T 0%
- Gujarati IndianT;T 6%
- Luhya (Kenya)T;T 14%
- Mexican ancestry (Los Angeles)T;T 0%
- Maasai (Kenya)T;T 16%
- TuscanT;T 3%
Related
Conditions, medicines and genes
Other TP53 SNPs
- rs28934578T;Tinfo@snpedia.com would like to hear from youVery important
- rs11540652C;TLi-Fraumeni Syndrome (predicted)Very important
- rs11575997C;TLi-Fraumeni Syndrome (predicted)Very important
- rs28934573C;GLi-Fraumeni Syndrome (predicted)Very important
- rs28934574C;GLi-Fraumeni Syndrome (predicted)Very important
- rs28934575C;TLi-Fraumeni Syndrome (predicted)Very important
- rs28934576C;TLi-Fraumeni Syndrome (predicted)Very important
- rs28934577A;CLi-Fraumeni Syndrome (predicted)Very important
Notes
From SNPedia
Notes
* rs2279744, rs1042522, rs17878362 and rs1625895 associated with high grade endometrial cancer
Source and license
Adapted from rs1625895 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.