rs1642785
A SNP in the TP53 gene on chromosome 17. Its most notable genotype is G;G: common in clinvar
- Gene
- TP53
- Location
- Chr 177,676,483 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- AncestryDNA
- Minor allele frequency
- 36%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs1642785 on the minus strand: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other TP53 SNPs
- rs28934578T;Tinfo@snpedia.com would like to hear from youVery important
- rs11540652C;TLi-Fraumeni Syndrome (predicted)Very important
- rs11575997C;TLi-Fraumeni Syndrome (predicted)Very important
- rs28934573C;GLi-Fraumeni Syndrome (predicted)Very important
- rs28934574C;GLi-Fraumeni Syndrome (predicted)Very important
- rs28934575C;TLi-Fraumeni Syndrome (predicted)Very important
- rs28934576C;TLi-Fraumeni Syndrome (predicted)Very important
- rs28934577A;CLi-Fraumeni Syndrome (predicted)Very important
Notes
From SNPedia
Notes
Germ-line genetic variation of TP53 in osteosarcoma. Construction of a high resolution linkage disequilibrium map to evaluate common genetic variation in TP53 and neural tube defect risk in an Irish population. Single nucleotide polymorphisms in the TP53 region and susceptibility to invasive epithelial ovarian cancer. TP53 polymorphisms in gliomas from Indian patients: Study of codon 72 genotype, rs1642785, rs1800370 and 16 base pair insertion in intron-3. Using epidemiology and genomics to understand osteosarcoma etiology.
Source and license
Adapted from rs1642785 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.