rs16969968(A;G)

Slightly higher risk for nicotine dependence, lower risk for cocaine dependence

Magnitude
2.5Worth knowing
Repute
Bad
Frequency
18%Average of 11 populations
On SNPedia
rs16969968(A;G)
Gene
CHRNA5

Frequency

Share of people with A;G in each HapMap population.

  • European ancestry (Utah)45%
  • Tuscan43%
  • Mexican ancestry (Los Angeles)35%
  • Gujarati Indian31%
  • Maasai (Kenya)17%
  • African ancestry (Southwest US)12%
  • Chinese (Denver)7%
  • Han Chinese (Beijing)5%
  • Japanese (Tokyo)4%
  • Luhya (Kenya)<1%
  • Yoruba (Nigeria)0%

Other genotypes of rs16969968

  1. A;AMost notableBadhigher risk for nicotine dependence, lower risk for cocaine dependenceImportant · 3.04% of people
  2. G;GNot ratednormalTypical · 0.077% of people

All about rs16969968

Source and license

Adapted from rs16969968(A;G) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.