rs16990018(A;G)

PrP 171 N/S Heterozygote - Unknown significance

Magnitude
1.0Minor
Repute
Not rated
Frequency
6%Average of 9 populations
On SNPedia
rs16990018(A;G)
Gene
PRNP

Frequency

Share of people with A;G in each HapMap population.

  • Luhya (Kenya)19%
  • Yoruba (Nigeria)12%
  • African ancestry (Southwest US)12%
  • Han Chinese (Beijing)3%
  • Tuscan2%
  • Mexican ancestry (Los Angeles)2%
  • Gujarati Indian1%
  • European ancestry (Utah)0%
  • Japanese (Tokyo)0%

Other genotypes of rs16990018

  1. A;AGoodPrP Codon 171 Asn - Non-pathogenic variantTypical · 0.094% of people
  2. G;GMost notableNot ratedNo summary available.Worth knowing · 2.0<1% of people

All about rs16990018

Notes

From SNPedia

This SNP indicates heterozygosity at Codon 171 of the Prion Protein. This SNP was recently determined to be more common than expected in healthy controls and so is now believed to be non-pathogenic.

References

Source and license

Adapted from rs16990018(A;G) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.