rs17036170(A;A)

Elevated risk for drug induced liver injury with diclofenac

Magnitude
2.0Worth knowing
Repute
Bad
Frequency
4%Average of 4 populations
On SNPedia
rs17036170(A;A)
Gene
PPARG

Frequency

Share of people with A;A in each HapMap population.

  • Tuscan7%
  • Mexican ancestry (Los Angeles)6%
  • African ancestry (Southwest US)2%
  • European ancestry (Utah)<1%

Other genotypes of rs17036170

  1. A;GBadIncreased risk of drug induced liver injury with diclofenacMinor · 1.996% of people
  2. G;GGoodcommon/normalTypical · 0.00% of people

All about rs17036170

Notes

From SNPedia

This uncommon risk allele A was found in a GWAS to be associated with drug induced liver injury with diclofenac. OR = 11.3 (4.9–25.9) Replicability is uncertain, but individuals with this genotype should be aware of the potential of increased risk. The odds ratio above is probably for heterozygotes, and it is not clear if the homozygous AA is worse, if in fact the risk can be replicated.

Source and license

Adapted from rs17036170(A;A) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.